Gtlela Direct

: A comprehensive review on Galleria mellonella as a Model for the Study of aPDT discusses how it's used to test light-based therapies (antimicrobial photodynamic therapy) against drug-resistant "superbugs".

: Despite being an insect, its innate immune system shows remarkable similarities to that of mammals, including specialized cells (hemocytes) that function like human neutrophils. Gtlela

The Virtuous Galleria mellonella Model for Scientific ... - PMC : A comprehensive review on Galleria mellonella as

: It allows researchers to follow the "3Rs" principle (Replacement, Reduction, and Refinement) by replacing vertebrate animals in early-stage studies. - PMC : It allows researchers to follow

: Unlike many other invertebrates, these larvae can survive at 37°C , which is the human body temperature, making them ideal for studying human pathogens like Candida albicans or Staphylococcus aureus .

: Newer papers highlight its excellence in studying fungal infections and evaluating the effectiveness of new antifungal drug candidates.

: They are inexpensive, easy to handle, and produce results within days rather than weeks. Recent Research Directions