Antifungal Agent May 2026
: Azoles inhibit the cytochrome P450-dependent enzyme lanosterol
: Fluconazole , itraconazole , and voriconazole . 2. Polyenes antifungal agent
-(1,3)-D-glucan, a major polysaccharide responsible for maintaining the structural integrity of the cell wall, causing cell lysis. and voriconazole . 2. Polyenes -(1
: This class targets the fungal cell wall rather than the membrane. They inhibit the enzyme -(1,3)-D-glucan synthase. Effect : This blocks the synthesis of antifungal agent