New regulators of ribosome biogenesis, transcription, and mitochondrial respiration were discovered, including CCDC86, ZNF236, and SPATA5L1.
The research uses transcriptional phenotypes to predict the function of poorly characterized genes.
Mapping information-rich genotype-phenotype landscapes ... - PMC
The study allows for in-depth dissection of complex cellular phenomena, including RNA processing and differentiation.
